| CAMPEONATO NACIONAL 2022 | ||||
| Campeonato de Apertura | ||||
| 1º Fecha | ||||
| 5-feb-2022 | Montevideo | Torque | 1 | Guerrero |
| Cerro Largo | 1 | Tizon | ||
| 5-feb-2022 | Montevideo | Fenix | 1 | Vega |
| Peñarol | 0 | |||
| 5-feb-2022 | Montevideo | Defensor Sporting | 0 | |
| Liverpool | 3 | Mallo (A), Vecino, Rodriguez | ||
| 6-feb-2022 | Montevideo | Albion | 3 | Rodriguez (2, 1P), Vargas |
| Rentistas | 5 | Juninho Rocha, Ibañez (A), Duarte (P), Acevedo, Barcia | ||
| 6-feb-2022 | Minas | Boston River | 0 | |
| Plaza Colonia | 0 | |||
| 6-feb-2022 | Montevideo | Nacional | 2 | Gigliotti, Zunino |
| Maldonado | 3 | Darias, Marichal (A), Cantera | ||
| 7-feb-2022 | Montevideo | River Plate | 1 | Borbas |
| Wanderers | 1 | Rivero | ||
| 8-feb-2022 | Montevideo | Cerrito | 0 | |
| Danubio | 1 | Evans | ||
| 2º Fecha | ||||
| 11-feb-2022 | Montevideo | Torque | 1 | Guerrero |
| Cerro Largo | 2 | Barboza, Estoyanoff | ||
| 12-feb-2022 | Colonia | Plaza Colonia | 0 | |
| del Sacramento | River Plate | 1 | Montiel | |
| 12-feb-2022 | Montevideo | Rentistas | 0 | |
| Nacional | 4 | Carballo, Monzeglio, Ocampo, Gabriel (A) | ||
| 13-feb-2022 | Montevideo | Liverpool | 4 | Diaz, Vecino, Carneiro, Medina |
| Albion | 0 | |||
| 13-feb-2022 | Minas | Boston River | 0 | |
| Cerrito | 1 | Rodriguez | ||
| 13-feb-2022 | Montevideo | Peñarol | 0 | |
| Defensor Sporting | 1 | Balboa | ||
| 14-feb-2022 | Montevideo | Wanderers | 1 | Mendez |
| Cerro Largo | 0 | |||
| 14-feb-2022 | Maldonado | Maldonado | 1 | Rodriguez |
| Danubio | 2 | Hernandez, Fernandez | ||
| 3º Fecha | ||||
| 18-feb-2022 | Maldonado | Cerro Largo | 0 | |
| Plaza Colonia | 5 | Rodriguez, Mereles, Bahia, Dibble (2) | ||
| 19-feb-2022 | Montevideo | River Plate | 1 | Lopez |
| Boston River | 2 | Rodriguez, Viega | ||
| 19-feb-2022 | Montevideo | Defensor Sporting | 1 | Barrios |
| Torque | 3 | Morales, Guerrero, Allende | ||
| 19-feb-2022 | Montevideo | Albion | 1 | Callorda |
| Peñarol | 1 | Ceppelini | ||
| 20-feb-2022 | Montevideo | Fenix | 0 | |
| Wanderers | 3 | Rivero, Mendez (P), Pais | ||
| 20-feb-2022 | Montevideo | Danubio | 0 | |
| Rentistas | 1 | Acevedo | ||
| 21-feb-2022 | Montevideo | Cerrito | 0 | |
| Maldonado | 3 | Velazquez (A), Quiroga, Borges (P) | ||
| 21-feb-2022 | Montevideo | Nacional | 0 | |
| Liverpool | 0 | |||
| 4º Fecha | ||||
| 25-feb-2022 | Minas | Boston River | 3 | Mancebo, Villa, Machado |
| Cerro Largo | 0 | |||
| 25-feb-2022 | Colonia | Plaza Colonia | 1 | Daniel Bahia |
| del Sacramento | Fenix | 1 | Estoyanoff (P) | |
| 26-feb-2022 | Montevideo | Rentistas | 1 | Guedes |
| Maldonado | 2 | Borges (2) | ||
| 26-feb-2022 | Montevideo | Liverpool | 0 | |
| Danubio | 1 | Cabrera | ||
| 26-feb-2022 | Montevideo | Wanderers | 1 | Mendez |
| Defensor Sporting | 0 | |||
| 27-feb-2022 | Montevideo | Peñarol | 1 | Ceppelini (P) |
| Nacional | 0 | |||
| 28-feb-2022 | Montevideo | River Plate | 3 | Vega (A), Ocampo, Galletto |
| Cerrito | 1 | Gonzalez | ||
| 28-feb-2022 | Montevideo | Torque | 1 | Guerrero |
| Albion | 2 | Arismendi (A), Barros | ||
| 5º Fecha | ||||
| 4-mar-2022 | Maldonado | Maldonado | 1 | Rodriguez (A) |
| Liverpool | 0 | |||
| 5-mar-2022 | Montevideo | River Plate | 1 | Salaberry |
| Cerro Largo | 1 | Max | ||
| 5-mar-2022 | Montevideo | Danubio | 0 | |
| Peñarol | 1 | Bentancourt (P) | ||
| 11-mar-2022 | Montevideo | Cerrito | 2 | Sosa, Rodriguez |
| Rentistas | 1 | Acevedo (P) | ||
| 12-mar-2022 | Montevideo | Fenix | 0 | |
| Boston River | 2 | Costa, Barja | ||
| 12-mar-2022 | Montevideo | Defensor Sporting | 0 | |
| Plaza Colonia | 0 | |||
| 13-mar-2022 | Montevideo | Albion | 1 | Neris |
| Wanderers | 1 | Mendez | ||
| 13-mar-2022 | Montevideo | Nacional | 1 | Fagundez |
| Torque | 1 | Arismendi | ||
| 6º Fecha | ||||
| 19-mar-2022 | Montevideo | Peñarol | 1 | Ramos |
| Maldonado | 1 | Borges | ||
| 19-mar-2022 | Colonia | Plaza Colonia | 1 | Ayala |
| del Sacramento | Albion | 1 | Neris | |
| 20-mar-2022 | Montevideo | Liverpool | 1 | Medina |
| Rentistas | 0 | |||
| 20-mar-2022 | Montevideo | River Plate | 3 | Borbas, Toledo (A), Castro |
| Fenix | 1 | Casas | ||
| 20-mar-2022 | Montevideo | Wanderers | 2 | Rivero, Hernandez |
| Nacional | 2 | Castro, Fagundez | ||
| 21-mar-2022 | Trinidad | Boston River | 1 | Lopez |
| Defensor Sporting | 1 | Navarro | ||
| 21-mar-2022 | Montevideo | Torque | 1 | Orihuela |
| Danubio | 1 | Tinaglini (A) | ||
| 22-mar-2022 | Montevideo | Cerro Largo | 1 | Morales |
| Cerrito | 0 | |||
| 7º Fecha | ||||
| 1-abr-2022 | Montevideo | Rentistas | 0 | |
| Peñarol | 0 | |||
| 2-abr-2022 | Montevideo | Albion | 1 | Noble |
| Boston River | 2 | Viega, Machado | ||
| 2-abr-2022 | Montevideo | Danubio | 0 | |
| Wanderers | 0 | |||
| 2-abr-2022 | Montevideo | Nacional | 1 | Zabala |
| Plaza Colonia | 0 | |||
| 2-abr-2022 | Montevideo | Defensor Sporting | 3 | Sant'Anna, Mendez, Navarro (P) |
| River Plate | 2 | Borbas (P), Sosa (P) | ||
| 3-abr-2022 | Montevideo | Fenix | 2 | Casas, Estoyanoff (P) |
| Cerro Largo | 0 | |||
| 3-abr-2022 | Montevideo | Cerrito | 0 | |
| Liverpool | 1 | Lemos | ||
| 3-abr-2022 | Maldonado | Maldonado | 2 | Aguiar (P), Cantera |
| Torque | 1 | Guzman | ||
| 8º Fecha | ||||
| 8-abr-2022 | Maldonado | Cerro Largo | 0 | |
| Defensor Sporting | 0 | |||
| 9-abr-2022 | Montevideo | Peñarol | 2 | Ceppelini, Laquintana |
| Liverpool | 1 | Medina | ||
| 9-abr-2022 | Colonia | Plaza Colonia | 1 | Rodriguez |
| del Sacramento | Danubio | 1 | May | |
| 10-abr-2022 | Montevideo | Fenix | 2 | Estoyanoff, Viera |
| Cerrito | 0 | |||
| 10-abr-2022 | Montevideo | River Plate | 4 | Chopitea, Aja, Sosa (2) |
| Albion | 1 | Ndong | ||
| 10-abr-2022 | Minas | Boston River | 0 | |
| Nacional | 6 | Carballo (3, 2P), Trezza, Zabala, Fagundez | ||
| 11-abr-2022 | Montevideo | Wanderers | 0 | |
| Maldonado | 1 | Borges (P) | ||
| 11-abr-2022 | Montevideo | Torque | 2 | Alvarez, Orihuela |
| Rentistas | 0 | |||
| 9º Fecha | ||||
| 15-abr-2022 | Montevideo | Danubio | 0 | |
| Boston River | 0 | |||
| 15-abr-2022 | Montevideo | Defensor Sporting | 2 | Elizari (2) |
| Fenix | 1 | De los Santos (A) | ||
| 16-abr-2022 | Montevideo | Liverpool | 2 | Pereira (2) |
| Torque | 0 | |||
| 16-abr-2022 | Montevideo | Albion | 2 | Papa, Noble |
| Cerro Largo | 1 | Max | ||
| 16-abr-2022 | Montevideo | Cerrito | 0 | |
| Peñarol | 0 | |||
| 17-abr-2022 | Maldonado | Maldonado | 3 | Romero, Piriz, Borges |
| Plaza Colonia | 1 | Barrandeguy (P) | ||
| 17-abr-2022 | Montevideo | Nacional | 1 | Ocampo |
| River Plate | 1 | Castro | ||
| 17-abr-2022 | Montevideo | Rentistas | 1 | Rocha |
| Wanderers | 3 | Ferreira, Mendez (2) | ||
| 10º Fecha | ||||
| 22-abr-2022 | Las Piedras | Cerro Largo | 0 | |
| Nacional | 2 | Monzeglio (2) | ||
| 23-abr-2022 | Montevideo | Wanderers | 0 | |
| Liverpool | 0 | |||
| 23-abr-2022 | Montevideo | River Plate | 0 | |
| Danubio | 0 | |||
| 23-abr-2022 | Montevideo | Torque | 0 | |
| Peñarol | 1 | Alvarez Martinez | ||
| 24-abr-2022 | Montevideo | Fenix | 2 | Schetino, Estoyanoff |
| Albion | 1 | Callorda (P) | ||
| 24-abr-2022 | Minas | Boston River | 2 | Machado, Fernandex |
| Maldonado | 0 | |||
| 24-abr-2022 | Colonia | Plaza Colonia | 0 | |
| del Sacramento | Rentistas | 3 | Silveira (2, 1P), Acosta | |
| 25-abr-2022 | Montevideo | Defensor Sporting | 0 | |
| Cerrito | 0 | |||
| 11º Fecha | ||||
| 6-may-2022 | Montevideo | Cerrito | 2 | Perujo (P), Velazquez |
| Torque | 2 | Allende, Palacios | ||
| 7-may-2022 | Montevideo | Albion | 0 | |
| Defensor Sporting | 3 | Balboa, Navarro, Mendez | ||
| 7-may-2022 | Montevideo | Liverpool | 1 | Perez |
| Plaza Colonia | 0 | |||
| 7-may-2022 | Maldonado | Maldonado | 2 | Anselmo (2) |
| River Plate | 1 | Ocampo | ||
| 8-may-2022 | Montevideo | Rentistas | 0 | |
| Boston River | 1 | Rodriguez | ||
| 8-may-2022 | Montevideo | Danubio | 2 | Hernandez, Silvera |
| Cerro Largo | 0 | |||
| 8-may-2022 | Montevideo | Peñarol | 1 | Ceppelini (P) |
| Wanderers | 0 | |||
| 9-may-2022 | Montevideo | Nacional | 1 | Monzeglio (P) |
| Fenix | 0 | |||
| 12º Fecha | ||||
| 13-may-2022 | Montevideo | River Plate | 1 | Borbas |
| Rentistas | 0 | |||
| 13-may-2022 | Colonia | Plaza Colonia | 0 | |
| del Sacramento | Peñarol | 1 | Ceppelini (P) | |
| 14-may-2022 | Montevideo | Defensor Sporting | 0 | |
| Nacional | 2 | Gigliotti, Candido | ||
| 14-may-2022 | Montevideo | Wanderers | 1 | Mendez |
| Torque | 1 | Allende | ||
| 15-may-2022 | Melo | Cerro Largo | 1 | Ramis |
| Maldonado | 0 | |||
| 15-may-2022 | Montevideo | Fenix | 0 | |
| Danubio | 0 | |||
| 15-may-2022 | Montevideo | Albion | 2 | Rodriguez, Pizzorno |
| Cerrito | 2 | Vila (2) | ||
| 16-may-2022 | Trinidad | Boston River | 2 | Lopez, Machado |
| Liverpool | 3 | Carneiro, Romero, Vecino | ||
| 13º Fecha | ||||
| 20-may-2022 | Maldonado | Maldonado | 0 | |
| Fenix | 1 | Casas | ||
| 21-may-2022 | Montevideo | Rentistas | 2 | Silveira (P), Varela |
| Cerro Largo | 0 | |||
| 21-may-2022 | Montevideo | Nacional | 2 | Rodriguez, Zabala |
| Albion | 0 | |||
| 21-may-2022 | Montevideo | Peñarol | 1 | Viatri |
| Boston River | 0 | |||
| 22-may-2022 | Montevideo | Liverpool | 2 | Rivero, Medina |
| River Plate | 1 | Castro | ||
| 22-may-2022 | Montevideo | Danubio | 1 | Rodriguez |
| Defensor Sporting | 2 | Navarro (P), Balboa (P) | ||
| 22-may-2022 | Montevideo | Cerrito | 0 | |
| Wanderers | 2 | Ferreira, Mendez | ||
| 23-may-2022 | Montevideo | Torque | 1 | Allende |
| Plaza Colonia | 1 | Bahia | ||
| 14º Fecha | ||||
| 27-may-2022 | Montevideo | Albion | 1 | Barrios |
| Danubio | 2 | May, Fernandez | ||
| 28-may-2022 | Melo | Cerro Largo | 1 | Ergas |
| Liverpool | 2 | Medina (P), Carneiro | ||
| 28-may-2022 | Trinidad | Boston River | 3 | Rodriguez (2), Costa |
| Torque | 1 | Guerrero | ||
| 28-may-2022 | Montevideo | Nacional | 3 | Gigliotti, Ramirez (2) |
| Cerrito | 0 | |||
| 29-may-2022 | Colonia | Plaza Colonia | 1 | Barrandeguy (P) |
| del Sacramento | Wanderers | 0 | ||
| 29-may-2022 | Montevideo | River Plate | 0 | |
| Peñarol | 0 | |||
| 29-may-2022 | Montevideo | Defensor Sporting | 1 | Labandeira |
| Maldonado | 1 | Borges | ||
| 30-may-2022 | Montevideo | Fenix | 2 | Godoy (A), Bueno (P) |
| Rentistas | 1 | Silveira | ||
| 15º Fecha | ||||
| 3-jun-2022 | Montevideo | Torque | 0 | |
| River Plate | 0 | |||
| 4-jun-2022 | Montevideo | Peñarol | 0 | |
| Cerro Largo | 1 | Tizon | ||
| 4-jun-2022 | Maldonado | Maldonado | 0 | |
| Albion | 0 | |||
| 4-jun-2022 | Montevideo | Cerrito | 1 | Pimienta |
| Plaza Colonia | 1 | Barrandeguy (P) | ||
| 5-jun-2022 | Montevideo | Rentistas | 1 | Acevedo |
| Defensor Sporting | 0 | |||
| 5-jun-2022 | Montevideo | Liverpool | 1 | Carneiro (P) |
| Fenix | 0 | |||
| 5-jun-2022 | Montevideo | Danubio | 2 | Haller, Rodriguez (P) |
| Nacional | 1 | Fagundez | ||
| 6-jun-2022 | Montevideo | Wanderers | 1 | Cosentino |
| Boston River | 2 | Rodriguez, Machado | ||
| Torneo Intermedio | ||||
| Grupo 1 | ||||
| 1º Fecha | ||||
| 10-jun-2022 | Montevideo | Rentistas | 1 | Silveira (P) |
| Maldonado | 1 | Varela | ||
| 12-jun-2022 | Montevideo | Wanderers | 1 | Vicente |
| Liverpool | 1 | Morales | ||
| 12-jun-2022 | Montevideo | Peñarol | 1 | Ramos (P) |
| Torque | 2 | Pereira, Nicola | ||
| 13-jun-2022 | Montevideo | Fenix | 0 | |
| Albion | 1 | Neris | ||
| 2º Fecha | ||||
| 18-jun-2022 | Montevideo | Albion | 1 | Pizzorno |
| Wanderers | 1 | Rivero | ||
| 18-jun-2022 | Montevideo | Liverpool | 2 | Carneiro, Gonzalez |
| Fenix | 2 | Sosa, Schetino | ||
| 19-jun-2022 | Montevideo | Torque | 3 | Palacios, Allende (2P) |
| Rentistas | 1 | Rolin | ||
| 19-jun-2022 | Maldonado | Maldonado | 1 | Arias (A) |
| Peñarol | 3 | Bentancourt, Laquintana, Ceppelini (P) | ||
| 3º Fecha | ||||
| 25-jun-2022 | Montevideo | Fenix | 0 | |
| Maldonado | 0 | |||
| 25-jun-2022 | Montevideo | Peñarol | 0 | |
| Liverpool | 1 | Gonzalez | ||
| 27-jun-2022 | Montevideo | Rentistas | 0 | |
| Albion | 1 | Rodriguez (P) | ||
| 27-jun-2022 | Montevideo | Wanderers | 1 | Cosentino |
| Torque | 0 | |||
| 4º Fecha | ||||
| 8-jul-2022 | Montevideo | Albion | 1 | Pizzorno |
| Torque | 0 | |||
| 9-jul-2022 | Maldonado | Maldonado | 1 | Borges |
| Wanderers | 2 | Mendez (2) | ||
| 9-jul-2022 | Montevideo | Liverpool | 2 | Rivero, Medina |
| Rentistas | 0 | |||
| 10-jul-2022 | Montevideo | Peñarol | 0 | |
| Fenix | 0 | |||
| 5º Fecha | ||||
| 14-jul-2022 | Montevideo | Torque | 2 | Palacios, Morales |
| Liverpool | 3 | Diaz, Medina, Vecino | ||
| 15-jul-2022 | Montevideo | Albion | 2 | Goyeni, Neris (P) |
| Maldonado | 3 | Cantera (2P), Piriz | ||
| 16-jul-2022 | Montevideo | Rentistas | 0 | |
| Fenix | 1 | Scorza | ||
| 16-jul-2022 | Montevideo | Wanderers | 3 | Bravo, Hernandez, Santurio |
| Peñarol | 3 | Bentancourt (3) | ||
| 6º Fecha | ||||
| 19-jul-2022 | Montevideo | Liverpool | 0 | |
| Albion | 0 | |||
| 19-jul-2022 | Maldonado | Maldonado | 1 | Cantera |
| Torque | 1 | Pereira | ||
| 20-jul-2022 | Montevideo | Fenix | 1 | Pereira |
| Wanderers | 0 | |||
| 20-jul-2022 | Montevideo | Peñarol | 2 | Rossi, Bentancourt (P) |
| (*) | Rentistas | 0 | ||
| (*) Partido interrumpido por corte de luz. Terminado de jugar el 26/7/2022 | ||||
| 7º Fecha | ||||
| 23-jul-2022 | Montevideo | Liverpool | 3 | Medina, Martirena, Soria (P) |
| Maldonado | 1 | Borges | ||
| 23-jul-2022 | Maldonado | Albion | 1 | Neris (P) |
| Peñarol | 3 | Ramos, laquintana, Saravia | ||
| 23-jul-2022 | Montevideo | Wanderers | 3 | Bravo, Ferreira, Santurio |
| Rentistas | 1 | Silveira | ||
| 24-jul-2022 | Montevideo | Torque | 2 | Barboza (A), Palacios |
| Fenix | 0 | |||
| Grupo 2 | ||||
| 1º Fecha | ||||
| 10-jun-2022 | Montevideo | River Plate | 3 | Adamo (2), Affonso |
| Cerrito | 0 | |||
| 12-jun-2022 | Montevideo | Danubio | 1 | Vicente |
| Cerro Largo | 1 | Morales | ||
| 13-jun-2022 | Montevideo | Defensor Sporting | 0 | |
| Nacional | 1 | Ramirez | ||
| 14-jun-2022 | Colonia | Plaza Colonia | 0 | |
| del Sacramento | Boston River | 0 | ||
| 2º Fecha | ||||
| 18-jun-2022 | Montevideo | Nacional | 3 | Gigliotti, Zabala, Lozano |
| River Plate | 0 | |||
| 19-jun-2022 | Montevideo | Cerrito | 1 | Falconis |
| Defensor Sporting | 2 | Boggio, Labandeira | ||
| 20-jun-2022 | Trinidad | Boston River | 2 | E. Rodriguez, A. Rodriguez |
| Danubio | 0 | |||
| 20-jun-2022 | Melo | Cerro Largo | 1 | Villar |
| Plaza Colonia | 0 | |||
| 3º Fecha | ||||
| 25-jun-2022 | Montevideo | Danubio | 0 | |
| Nacional | 1 | Rodriguez | ||
| 25-jun-2022 | Montevideo | Defensor Sporting | 1 | Labandeira |
| Cerro Largo | 0 | |||
| 26-jun-2022 | Montevideo | River Plate | 0 | |
| Boston River | 1 | Rodriguez | ||
| 26-jun-2022 | Colonia | Plaza Colonia | 3 | Barrandeguy (P), Quintana, Bahia |
| del Sacramento | Cerrito | 0 | ||
| 4º Fecha | ||||
| 9-jul-2022 | Montevideo | Nacional | 3 | Leo Coelho, Trezza, Zabala |
| Plaza Colonia | 1 | Quintana (P) | ||
| 10-jul-2022 | Montevideo | Danubio | 1 | Fernandez |
| River Plate | 3 | Borbas (2, 1P), Ocampo | ||
| 10-jul-2022 | Trinidad | Boston River | 2 | Fernandez Benitez, Rodriguez |
| Defensor Sporting | 3 | Balboa, Duarte, Sant'Anna | ||
| 11-jul-2022 | Montevideo | Cerrito | 0 | |
| Cerro Largo | 2 | Villar, Bengeche | ||
| 5º Fecha | ||||
| 15-jul-2022 | Colonia | Plaza Colonia | 0 | |
| del Sacramento | River Plate | 0 | ||
| 16-jul-2022 | Trinidad | Boston River | 1 | Rodriguez |
| Cerrito | 0 | |||
| 17-jul-2022 | Melo | Cerro Largo | 0 | |
| Nacional | 0 | |||
| 17-jul-2022 | Montevideo | Defensor Sporting | 2 | Sant'Anna, Ferrari |
| Danubio | 1 | Gonzalez | ||
| 6º Fecha | ||||
| 20-jul-2022 | Trinidad | Boston River | 2 | Romero (A), Costa |
| Cerro Largo | 0 | |||
| 21-jul-2022 | Montevideo | Danubio | 2 | Vicente (2) |
| Plaza Colonia | 0 | |||
| 21-jul-2022 | Montevideo | River Plate | 1 | Borbas |
| Defensor Sporting | 1 | Balboa | ||
| 21-jul-2022 | Montevideo | Nacional | 5 | Gigliotti (2), Fagundez, Carballo, Almeida |
| Cerrito | 0 | |||
| 7º Fecha | ||||
| 24-jul-2022 | Montevideo | Defensor Sporting | 1 | Balboa (P) |
| Plaza Colonia | 2 | Quintana, Mederos | ||
| 24-jul-2022 | Montevideo | Nacional | 2 | Gigliotti, Fagundez |
| Boston River | 0 | |||
| 25-jul-2022 | Montevideo | Cerrito | 0 | |
| Danubio | 1 | Hernandez | ||
| 25-jul-2022 | Melo | Cerro Largo | 0 | |
| River Plate | 0 | |||
| Final | ||||
| 27-jul-2022 | Montevideo | Liverpool | 0 | |
| Nacional | 1 | Rodriguez | ||
| Campeonato de Clausura | ||||
| 1º Fecha | ||||
| 30-jul-2022 | Montevideo | Rentistas | 2 | Jumbeltz, Silveira |
| Albion | 4 | Neris (3, 1P), Rodriguez | ||
| 30-jul-2022 | Colonia | Plaza Colonia | 1 | Ebere |
| del Sacramento | Boston River | 1 | Machado | |
| 30-jul-2022 | Maldonado | Maldonado | 2 | Cantera (2) |
| Nacional | 1 | Ramirez | ||
| 31-jul-2022 | Montevideo | Danubio | 0 | |
| Cerrito | 0 | |||
| 31-jul-2022 | Melo | Cerro Largo | 1 | Villar |
| Torque | 2 | Ribas, Palacios | ||
| 31-jul-2022 | Montevideo | Wanderers | 1 | Santurio |
| River Plate | 2 | Borbas (2, 1P) | ||
| 1-ago-2022 | Montevideo | Liverpool | 1 | Rodriguez (P) |
| Defensor Sporting | 3 | Balboa, Ocampo, Valiente | ||
| 1-ago-2022 | Montevideo | Peñarol | 0 | |
| Fenix | 1 | Vega (P) | ||
| 2º Fecha | ||||
| 5-ago-2022 | Montevideo | Nacional | 3 | Rodriguez, Ramirez, Suarez |
| Rentistas | 0 | |||
| 6-ago-2022 | Montevideo | River Plate | 2 | Borbas, Urretaviscaya |
| Plaza Colonia | 0 | |||
| 6-ago-2022 | Melo | Cerro Largo | 1 | Beltran |
| Wanderers | 1 | Ferreira | ||
| 6-ago-2022 | Montevideo | Cerrito | 0 | |
| Boston River | 3 | Rodriguez (2), Lopez | ||
| 7-ago-2022 | Montevideo | Fenix | 1 | Triunfo |
| Torque | 0 | |||
| 7-ago-2022 | Montevideo | Danubio | 0 | |
| Maldonado | 0 | |||
| 7-ago-2022 | Montevideo | Defensor Sporting | 2 | Balboa, Mallo |
| Peñarol | 3 | Mendez, Laquintana, Ramos | ||
| 8-ago-2022 | Montevideo | Albion | 1 | Platero |
| Liverpool | 1 | Rivero | ||
| 3º Fecha | ||||
| 11-ago-2022 | Montevideo | Maldonado | 2 | Cotugno, Cantera |
| Cerrito | 1 | Correa | ||
| 11-ago-2022 | Montevideo | Wanderers | 2 | Ferreira, Hernandez |
| Fenix | 1 | Vega (P) | ||
| 12-ago-2022 | Montevideo | Boston River | 1 | Rodriguez (P) |
| River Plate | 2 | Lavega, Ocampo | ||
| 12-ago-2022 | Colonia | Plaza Colonia | 2 | Quintana (2, 1P) |
| del Sacramento | Cerro Largo | 0 | ||
| 13-ago-2022 | Montevideo | Rentistas | 0 | |
| Danubio | 1 | Fernandez | ||
| 13-ago-2022 | Montevideo | Peñarol | 2 | Pizzorno (2P) |
| Albion | 0 | |||
| 14-ago-2022 | Montevideo | Torque | 0 | |
| Defensor Sporting | 2 | Sant'Anna, Mallo | ||
| 14-ago-2022 | Montevideo | Liverpool | 0 | |
| Nacional | 1 | Fagundez | ||
| 4º Fecha | ||||
| 2-sep-2022 | Maldonado | Maldonado | 2 | Cayetano, Camarda |
| Rentistas | 1 | Rodriguez | ||
| 3-sep-2022 | Montevideo | Albion | 1 | Neris (P) |
| Torque | 0 | |||
| 3-sep-2022 | Montevideo | Danubio | 1 | Spetale |
| Liverpool | 1 | Vecino (P) | ||
| 3-sep-2022 | Montevideo | Defensor Sporting | 1 | Freitas |
| Wanderers | 0 | |||
| 4-sep-2022 | Montevideo | Nacional | 3 | Laborda, Suarez, Candido |
| Peñarol | 1 | Mendez | ||
| 4-sep-2022 | Melo | Cerro Largo | 1 | Viega (A) |
| Boston River | 1 | Mancebo | ||
| 5-sep-2022 | Montevideo | Cerrito | 1 | Klingender |
| River Plate | 5 | Lopez, Canosa (A), Borbas (2), De los Santos | ||
| 5-sep-2022 | Montevideo | Fenix | 0 | |
| Plaza Colonia | 1 | Jourdan | ||
| 5º Fecha | ||||
| 26-ago-2022 | Trinidad | Boston River | 1 | Rodriguez (P) |
| Fenix | 1 | Alfaro | ||
| 27-ago-2022 | Montevideo | Wanderers | 0 | |
| Albion | 0 | |||
| 27-ago-2022 | Montevideo | Rentistas | 3 | Godoy, Acuña (P), Acevedo (P) |
| Cerrito | 0 | |||
| 27-ago-2022 | Montevideo | Torque | 0 | |
| Nacional | 4 | Fagundez, Suarez, Gigliotti | ||
| 28-ago-2022 | Montevideo | Liverpool | 1 | Rivero |
| Maldonado | 1 | Cantera (P) | ||
| 28-ago-2022 | Colonia | Plaza Colonia | 0 | |
| del Sacramento | Defensor Sporting | 1 | Navarro | |
| 28-ago-2022 | Montevideo | Peñarol | 1 | Lozano |
| Danubio | 1 | May | ||
| 29-ago-2022 | Melo | Cerro Largo | 0 | |
| River Plate | 5 | Borbas, Lopez, Ocampo, De los Santos, Ergas (A) | ||
| 6º Fecha | ||||
| 19-ago-2022 | Montevideo | Danubio | 3 | Fernandez, Spetale, May |
| Torque | 2 | Ribas, Rabuñal | ||
| 19-ago-2022 | Montevideo | Cerrito | 0 | |
| Cerro Largo | 0 | |||
| 20-ago-2022 | Montevideo | Rentistas | 0 | |
| Liverpool | 2 | Medina, Vecino | ||
| 20-ago-2022 | Montevideo | Fenix | 1 | Vega (P) |
| River Plate | 2 | Borbas, De los Santos | ||
| 20-ago-2022 | Montevideo | Nacional | 2 | Carballo (2) |
| Wanderers | 0 | |||
| 21-ago-2022 | Montevideo | Defensor Sporting | 0 | |
| Boston River | 1 | Rodriguez | ||
| 22-ago-2022 | Montevideo | Albion | 1 | Ancheta |
| Plaza Colonia | 0 | |||
| 22-ago-2022 | Paysandu | Maldonado | 1 | Viatri (A) |
| Peñarol | 1 | Rak | ||
| 7º Fecha | ||||
| 9-sep-2022 | Montevideo | Liverpool | 3 | Vecino (2), Pereira |
| Cerrito | 0 | |||
| 9-sep-2022 | Montevideo | Torque | 3 | Morales, Palacios, Arismendi |
| Maldonado | 3 | Zeballos, Camarda, Cantera | ||
| 10-sep-2022 | Montevideo | Wanderers | 0 | |
| Danubio | 3 | Fernandez (3) | ||
| 10-sep-2022 | Trinidad | Boston River | 1 | Rodriguez |
| Albion | 0 | |||
| 10-sep-2022 | Colonia | Plaza Colonia | 1 | Redin |
| del Sacramento | Nacional | 3 | Rodriguez, Suarez, Zabala | |
| 11-sep-2022 | Montevideo | River Plate | 0 | |
| Defensor Sporting | 1 | Balboa | ||
| 11-sep-2022 | Melo | Cerro Largo | 1 | Villar |
| Fenix | 0 | |||
| 11-sep-2022 | Montevideo | Peñarol | 2 | Viatri (2) |
| Rentistas | 2 | Acevedo, Acuña | ||
| 8º Fecha | ||||
| 13-sep-2022 | Montevideo | Danubio | 1 | Navarro |
| Plaza Colonia | 1 | Mederos | ||
| 13-sep-2022 | Maldonado | Maldonado | 1 | Romero |
| Wanderers | 0 | |||
| 14-sep-2022 | Montevideo | Rentistas | 3 | Varela, Acuña, Buschiazzo |
| Torque | 0 | |||
| 14-sep-2022 | Montevideo | Albion | 0 | |
| River Plate | 2 | Borbas, Montiel | ||
| 14-sep-2022 | Montevideo | Nacional | 1 | Candido |
| Boston River | 0 | |||
| 15-sep-2022 | Montevideo | Cerrito | 0 | |
| Fenix | 2 | Cabrera, Pereira | ||
| 15-sep-2022 | Montevideo | Liverpool | 0 | |
| Peñarol | 1 | Mansilla | ||
| 15-sep-2022 | Montevideo | Defensor Sporting | 0 | |
| Cerro Largo | 1 | Miranda (P) | ||
| 9º Fecha | ||||
| 17-sep-2022 | Colonia | Plaza Colonia | 0 | |
| del Sacramento | Maldonado | 1 | Cantera (P) | |
| 17-sep-2022 | Montevideo | River Plate | 1 | Borbas |
| Nacional | 1 | Laborda | ||
| 17-sep-2022 | Montevideo | Wanderers | 1 | Milan |
| Rentistas | 0 | |||
| 18-sep-2022 | Melo | Cerro Largo | 1 | Villar |
| Albion | 2 | Callorda, Cruz | ||
| 18-sep-2022 | Montevideo | Peñarol | 3 | Bentancourt (2P), Busquets |
| Cerrito | 1 | Scarone | ||
| 19-sep-2022 | Trinidad | Boston River | 0 | |
| Danubio | 1 | Gonzalez | ||
| 19-sep-2022 | Montevideo | Torque | 0 | |
| Liverpool | 2 | Cougo, Pereira | ||
| 20-sep-2022 | Montevideo | Fenix | 0 | |
| Defensor Sporting | 0 | |||
| 10º Fecha | ||||
| 23-sep-2022 | Maldonado | Maldonado | 2 | Darias, Camarda |
| Boston River | 1 | Gomez | ||
| 24-sep-2022 | Montevideo | Liverpool | 1 | Vecino |
| Wanderers | 1 | Fracchia | ||
| 24-sep-2022 | Montevideo | Danubio | 3 | May, Silva, Oiivera |
| River Plate | 0 | |||
| 24-sep-2022 | Montevideo | Peñarol | 0 | |
| Torque | 1 | Palavecino | ||
| 25-sep-2022 | Montevideo | Rentistas | 0 | |
| Plaza Colonia | 1 | Perez | ||
| 25-sep-2022 | Montevideo | Nacional | 1 | Gigliotti (P) |
| Cerro Largo | 1 | Beltran | ||
| 25-sep-2022 | Montevideo | Cerrito | 1 | Demarco |
| Defensor Sporting | 2 | Sastre (A), Sant'Anna | ||
| 26-sep-2022 | Montevideo | Albion | 1 | Neris |
| Fenix | 1 | Scorza | ||
| 11º Fecha | ||||
| 30-sep-2022 | Melo | Cerro Largo | 1 | Tizon |
| Danubio | 0 | |||
| 30-sep-2022 | Colonia | Plaza Colonia | 1 | Kidd |
| del Sacramento | Liverpool | 3 | Cayetano, Vecino (2) | |
| 1-oct-2022 | Montevideo | Torque | 0 | |
| Cerrito | 1 | Correa | ||
| 1-oct-2022 | Montevideo | Fenix | 1 | Fernandez |
| Nacional | 1 | Leo Coelho | ||
| 1-oct-2022 | Montevideo | Defensor Sporting | 2 | Matturro, Ocampo |
| Albion | 0 | |||
| 2-oct-2022 | Montevideo | River Plate | 0 | |
| Maldonado | 0 | |||
| 2-oct-2022 | Trinidad | Boston River | 3 | Rodriguez (2P), Fernandez |
| Rentistas | 0 | |||
| 2-oct-2022 | Montevideo | Wanderers | 0 | |
| Peñarol | 2 | Rak, Laquintana | ||
| 12º Fecha | ||||
| 7-oct-2022 | Maldonado | Maldonado | 0 | |
| Cerro Largo | 1 | Tizon | ||
| 7-oct-2022 | Montevideo | Cerrito | 0 | |
| Albion | 0 | |||
| 8-oct-2022 | Montevideo | Rentistas | 0 | |
| River Plate | 5 | Borbas (2, 1P), Ocampo (2), Clar | ||
| 8-oct-2022 | Montevideo | Danubio | 1 | Hernandez |
| Fenix | 1 | Viera | ||
| 8-oct-2022 | Montevideo | Nacional | 1 | Trezza |
| Defensor Sporting | 1 | Abaldo | ||
| 9-oct-2022 | Montevideo | Torque | 1 | Ribas |
| Wanderers | 0 | |||
| 9-oct-2022 | Montevideo | Liverpool | 3 | Medina (2), Diaz |
| Boston River | 2 | Olivera, Mancebo | ||
| 9-oct-2022 | Montevideo | Peñarol | 0 | |
| Plaza Colonia | 1 | Mederos | ||
| 13º Fecha | ||||
| 11-oct-2022 | Montevideo | Fenix | 0 | |
| Maldonado | 1 | Camarda | ||
| 11-oct-2022 | Melo | Cerro Largo | 2 | Franco, Correa |
| Rentistas | 1 | Acevedo | ||
| 12-oct-2022 | Colonia | Plaza Colonia | 0 | |
| del Sacramento | Torque | 2 | Cejas (P), Orihuela | |
| 12-oct-2022 | Montevideo | Boston River | 2 | Olivera, Rodriguez (P) |
| Peñarol | 1 | Rossi | ||
| 12-oct-2022 | Montevideo | Defensor Sporting | 1 | Sant'Anna |
| Danubio | 1 | Rea | ||
| 13-oct-2022 | Montevideo | River Plate | 0 | |
| Liverpool | 1 | Rodriguez | ||
| 13-oct-2022 | Montevideo | Albion | 0 | |
| Nacional | 1 | Suarez | ||
| 13-oct-2022 | Montevideo | Wanderers | 2 | Milan (P), Mana |
| Cerrito | 1 | Scarone | ||
| 14º Fecha | ||||
| 15-oct-2022 | Montevideo | Rentistas | 1 | Acuña |
| Fenix | 3 | Pereira (2), Veiga | ||
| 15-oct-2022 | Maldonado | Maldonado | 0 | |
| Defensor Sporting | 0 | |||
| 16-oct-2022 | Montevideo | Liverpool | 1 | Rodriguez |
| Cerro Largo | 0 | |||
| 16-oct-2022 | Montevideo | Danubio | 3 | May (2), Olivera (P) |
| Albion | 0 | |||
| 16-oct-2022 | Montevideo | Peñarol | 1 | Bentancourt (P) |
| River Plate | 1 | Cristobal | ||
| 17-oct-2022 | Montevideo | Torque | 0 | |
| Boston River | 2 | Olivera (2) | ||
| 17-oct-2022 | Montevideo | Wanderers | 2 | Mana, Castro |
| Plaza Colonia | 1 | Ebere | ||
| 17-oct-2022 | Montevideo | Cerrito | 1 | Perujo |
| Nacional | 2 | Fagundez, Carballo | ||
| 15º Fecha | ||||
| 21-oct-2022 | Montevideo | River Plate | 2 | Sosa, Brunelli |
| Torque | 1 | Guruceaga (P) | ||
| 22-oct-2022 | Montevideo | Defensor Sporting | 2 | Balboa, Elizari |
| Rentistas | 3 | Fernandez, Godoy (P), Juninho Rocha | ||
| 22-oct-2022 | Melo | Cerro Largo | 0 | |
| Peñarol | 2 | Saravia, Mendez | ||
| 23-oct-2022 | Colonia | Plaza Colonia | 1 | Perez (P) |
| del Sacramento | Cerrito | 3 | Pimienta, Acevedo, Perez (A) | |
| 23-oct-2022 | Montevideo | Fenix | 0 | |
| Liverpool | 3 | Vecino (3, 2P) | ||
| 23-oct-2022 | Montevideo | Nacional | 2 | Fagundez, Suarez |
| Danubio | 0 | |||
| 24-oct-2022 | Trinidad | Boston River | 2 | Cordara, Rodriguez |
| Wanderers | 2 | Veglio, Hernandez | ||
| 24-oct-2022 | Montevideo | Albion | 1 | Izquierdo |
| Maldonado | 3 | Camarda, Darias, Borges | ||
| Semifinales | ||||
| 30-oct-2022 | Montevideo | Liverpool | 1 | Vecino (P) |
| Nacional | 4 | Suarez (2), Gigliotti (2) | ||